BDBM33413 benzo[7]annulene-8-carboxylic acid, 5

SMILES OC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1

InChI Key InChIKey=XCSLJQFPTAZKDV-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 33413   

TargetG-protein coupled receptor 35(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataEC50:  54nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataIC50:  110nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataEC50:  1.24E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactmas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed